Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 5
Introduction 6
Global Markets Direct Report Coverage 6
AIDS - Related Kaposi''s Sarcoma Overview 7
Therapeutics Development 8
An Overview of Pipeline Products for AIDS - Related Kaposi''s Sarcoma 8
AIDS - Related Kaposi''s Sarcoma Therapeutics under Development by Companies 10
AIDS - Related Kaposi''s Sarcoma Therapeutics under Investigation by Universities/Institutes 11
Mid Clinical Stage Products 13
Comparative Analysis 13
Early Clinical Stage Products 14
Comparative Analysis 14
Pre-Clinical Stage Products 15
Comparative Analysis 15
AIDS - Related Kaposi''s Sarcoma Therapeutics – Products under Development by Companies 16
AIDS - Related Kaposi''s Sarcoma Therapeutics – Products under Investigation by Universities/Institutes 17
Companies Involved in AIDS - Related Kaposi''s Sarcoma Therapeutics Development 18
Aphios Corporation 18
Azaya Therapeutics, Inc. 19
PTC Therapeutics, Inc. 20
Arisyn Therapeutics Inc. 21
AIDS - Related Kaposi''s Sarcoma – Therapeutics Assessment 22
Assessment by Monotherapy Products 22
Assessment by Combination Products 23
Assessment by Route of Administration 24
Assessment by Molecule Type 26
Drug Profiles 28
Dermos - Drug Profile 28
Product Description 28
Mechanism of Action 28
R&D Progress 28
PTC299 - Drug Profile 29
Product Description 29
Mechanism of Action 29
R&D Progress 29
ATI 0607 - Drug Profile 31
Product Description 31
Mechanism of Action 31
R&D Progress 31
Rapamycin - Drug Profile 32
Product Description 32
Mechanism of Action 32
R&D Progress 32
Bevacizumab - Drug Profile 33
Product Description 33
Mechanism of Action 33
R&D Progress 33
Gleevec - Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
SU5416 - Drug Profile 35
Product Description 35
Mechanism of Action 35
R&D Progress 35
Bortezomib - Drug Profile 36
Product Description 36
Mechanism of Action 36
R&D Progress 36
Lenalidomide - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
Halofuginone Hydrobromide - Drug Profile 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
Interferon beta-1b + Zidovudine - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
Lenalidomide - Drug Profile 40
Product Description 40
Mechanism of Action 40
R&D Progress 40
HAART + Bevacizumab - Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 42
ATI-0918 - Drug Profile 43
Product Description 43
Mechanism of Action 43
R&D Progress 43
AIDS - Related Kaposi''s Sarcoma Therapeutics – Drug Profile Updates 44
AIDS - Related Kaposi''s Sarcoma Therapeutics - Dormant Products 45
AIDS - Related Kaposi''s Sarcoma – Product Development Milestones 49
Featured News & Press Releases 49
Aug 05, 1997: Taxol Approved for Kaposi''s Sarcoma 49
Appendix 50
Methodology 50
Coverage 50
Secondary Research 50
Primary Research 50
Expert Panel Validation 50
Contact Us 51
Disclaimer 51
List of Tables
Number of Products Under Development for AIDS - Related Kaposi''s Sarcoma, H2 2012 8
Products under Development for AIDS - Related Kaposi''s Sarcoma – Comparative Analysis, H2 2012 9
Number of Products under Development by Companies, H2 2012 10
Number of Products under Investigation by Universities/Institutes, H2 2012 12
Comparative Analysis by Mid Clinical Stage Development, H2 2012 13
Comparative Analysis by Early Clinical Stage Development, H2 2012 14
Comparative Analysis by Pre-Clinical Stage Development, H2 2012 15
Products under Development by Companies, H2 2012 16
Products under Investigation by Universities/Institutes, H2 2012 17
Aphios Corporation, H2 2012 18
Azaya Therapeutics, Inc., H2 2012 19
PTC Therapeutics, Inc., H2 2012 20
Arisyn Therapeutics Inc., H2 2012 21
Assessment by Monotherapy Products, H2 2012 22
Assessment by Combination Products, H2 2012 23
Assessment by Stage and Route of Administration, H2 2012 25
Assessment by Stage and Molecule Type, H2 2012 27
AIDS - Related Kaposi''s Sarcoma Therapeutics – Drug Profile Updates 44
AIDS - Related Kaposi''s Sarcoma Therapeutics – Dormant Products 45
AIDS - Related Kaposi''s Sarcoma Therapeutics – Dormant Products (Contd..1) 46
AIDS - Related Kaposi''s Sarcoma Therapeutics – Dormant Products (Contd..2) 47
AIDS - Related Kaposi''s Sarcoma Therapeutics – Dormant Products (Contd..3) 48
List of Figures
Number of Products under Development for AIDS - Related Kaposi''s Sarcoma, H2 2012 8
Products under Development for AIDS - Related Kaposi''s Sarcoma – Comparative Analysis, H2 2012 9
Products under Development by Companies, H2 2012 10
Products under Investigation by Universities/Institutes, H2 2012 11
Mid Clinical Stage Products, H2 2012 13
Early Clinical Stage Products, H2 2012 14
Pre-Clinical Stage Products, H2 2012 15
Assessment by Monotherapy Products, H2 2012 22
Assessment by Combination Products, H2 2012 23
Assessment by Route of Administration, H2 2012 24
Assessment by Stage and Route of Administration, H2 2012 25
Assessment by Molecule Type, H2 2012 26
Assessment by Stage and Molecule Type, H2 2012 27