Table of Contents
Table of Contents 2
List of Tables 3
List of Figures 4
Introduction 5
Global Markets Direct Report Coverage 5
Acute Lymphoblastic Lymphoma Overview 6
Therapeutics Development 7
An Overview of Pipeline Products for Acute Lymphoblastic Lymphoma 7
Acute Lymphoblastic Lymphoma Therapeutics under Development by Companies 9
Acute Lymphoblastic Lymphoma Therapeutics under Investigation by Universities/Institutes 10
Mid Clinical Stage Products 11
Comparative Analysis 11
Early Clinical Stage Products 12
Comparative Analysis 12
Acute Lymphoblastic Lymphoma Therapeutics – Products under Development by Companies 13
Acute Lymphoblastic Lymphoma Therapeutics – Products under Investigation by Universities/Institutes 14
Companies Involved in Acute Lymphoblastic Lymphoma Therapeutics Development 15
Bristol-Myers Squibb Company 15
Acute Lymphoblastic Lymphoma – Therapeutics Assessment 16
Assessment by Monotherapy Products 16
Assessment by Combination Products 17
Assessment by Route of Administration 18
Assessment by Molecule Type 20
Drug Profiles 22
Therapeutic Allogeneic Lymphocytes - Drug Profile 22
Product Description 22
Mechanism of Action 22
R&D Progress 22
Hyper-CVAD + Filgrastim + Nelarabine - Drug Profile 23
Product Description 23
Mechanism of Action 23
R&D Progress 24
Rituximab + Carboplatin + Etoposide + Ifosfamide + Vorinostat - Drug Profile 26
Product Description 26
Mechanism of Action 26
R&D Progress 27
Rituximab - Drug Profile 28
Product Description 28
Mechanism of Action 28
R&D Progress 28
BMS-906024 - Drug Profile 29
Product Description 29
Mechanism of Action 29
R&D Progress 29
Acute Lymphoblastic Lymphoma Therapeutics - Dormant Products 30
Acute Lymphoblastic Lymphoma – Product Development Milestones 31
Featured News & Press Releases 31
Dec 13, 2011: Immunomedics Announces Results From Phase II Trial Of Epratuzumab At Hematology Conference 31
Dec 11, 2011: Micromet''s Blinatumomab Produces Durable Responses in Patients with Relapsed Diffuse Large B Cell Lymphoma 31
Appendix 33
Methodology 33
Coverage 33
Secondary Research 33
Primary Research 33
Expert Panel Validation 33
Contact Us 34
Disclaimer 34
List of Tables
Number of Products Under Development for Acute Lymphoblastic Lymphoma, H2 2012 7
Products under Development for Acute Lymphoblastic Lymphoma – Comparative Analysis, H2 2012 8
Number of Products under Development by Companies, H2 2012 9
Number of Products under Investigation by Universities/Institutes, H2 2012 10
Comparative Analysis by Mid Clinical Stage Development, H2 2012 11
Comparative Analysis by Early Clinical Stage Development, H2 2012 12
Products under Development by Companies, H2 2012 13
Products under Investigation by Universities/Institutes, H2 2012 14
Bristol-Myers Squibb Company, H2 2012 15
Assessment by Monotherapy Products, H2 2012 16
Assessment by Combination Products, H2 2012 17
Assessment by Stage and Route of Administration, H2 2012 19
Assessment by Stage and Molecule Type, H2 2012 21
Acute Lymphoblastic Lymphoma Therapeutics – Dormant Products 30
List of Figures
Number of Products under Development for Acute Lymphoblastic Lymphoma, H2 2012 7
Products under Development for Acute Lymphoblastic Lymphoma – Comparative Analysis, H2 2012 8
Products under Development by Companies, H2 2012 9
Products under Investigation by Universities/Institutes, H2 2012 10
Mid Clinical Stage Products, H2 2012 11
Early Clinical Stage Products, H2 2012 12
Assessment by Monotherapy Products, H2 2012 16
Assessment by Combination Products, H2 2012 17
Assessment by Route of Administration, H2 2012 18
Assessment by Stage and Route of Administration, H2 2012 19
Assessment by Molecule Type, H2 2012 20
Assessment by Stage and Molecule Type, H2 2012 21